COMAR CRM FACTSHEET

PT NAME

Trust

ASPARTATE TRANSAMINASE (AST) (catalytic activity concentration)     ERM-AD457/IFCC from JRC Geel

Material

Pure standards (crystalline or in solution)

Properties

Property	Property Value	Unit
	101.9 - 107.3	U/L
	1.69 - 1.79	µkat/L

1 - 2

Properties in bold italic are only indicative

Remarks

Cm Remarks

Aspartate Transaminase (AST) The certified reference material is a lyophilised powder from 1.0 mL of recombinant AST from E. coli in a pH 7.5 buffer containing bovine serum albumin, pyridoxal-phosphate, saccharose and antibiotics. It is filled in a glass vial equipped with a rubber stopper and an aluminium cap allowing direct reconstitution by injection through the septum. The vial is under slight underpressure of Argon (800 mbar). Unopened vials should be stored at - 20 °C ± 5 °C. After reconstitution, the material should be used within 6 hours, as it was verified that changes to the certified concentration observed during that period at ambient temperature are not significant. It is advisable to cover the vial with the original seal and to store it at 2 to 8 °C if the reconstituted material must be stored for 6 hours before use. *** For more information see https://crm.jrc.ec.europa.eu/p/ERM-AD457_IFCC *** Additional keywords: ASAT, AST, enzymes, laboratory medicine

Intended use

Cm Use

The material is primarily intended to be used to control the performance of the IFCC reference procedure for the determination of AST at 37 °C. When the material is used as a calibrant in a particular measurement procedure the commutability should be verified for the assay concerned.

Producer

Full name

European Commission - Joint Research Centre

Address

Retieseweg 111, B-2440 GEEL

Country

Belgium

Website

Webshop

jrc-rm-distribution@ec.europa.eu

Trust indicators

JRC Geel lists 671 materials on COMAR, of which

      665 materials are accompanied by a certificate cf. ISO 17034

       0 materials are linked to statutory activities as an NMI or a DI

       274 materials have been produced under a valid ISO 17034 accreditation (scope | certificate)

Ask the coordinator

If you find any mistakes please contact the RM Producer, jrc-rm-distribution@ec.europa.eu
ID: 100500 | Last revision: 2022-11-24 | Direct link to this Fact sheet

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